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KMID : 1039620130030020147
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Korean Journal of Family Practice
2013 Volume.3 No. 2 p.147 ~ p.152
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Screening of Gastric Cancer
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Bae Su-Hyun
Cho Be-long
Park Sang-Min
Lee Duck-Joo
Kim Kwang-Min
Lee Seung-Hwa
Lee Jung-Un
Lee Dong-Ryul
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Abstract
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In view of the high incidence of gastric cancer in South Korea, early detection of gastric cancer is very important. In recent years, the detection rate of early gastric cancer has increased steadily, even in patients without symptoms. As early detection and treatment can increase survival rates, the national cancer screening program has included screening of gastric cancer. Endoscopy counts as a more useful diagnostic tool than an upper gastointestinal (GI) series for high sensitivity and specifi city. Also, endoscopic examination can get tissues from the pathologic lesion and sometimes perform endoscopic treatment such endoscopic mucosal resection and endoscopic submucosal dissection, if indicated. Thus, using endoscopy for screening gastric cancer is the most effective tool. However, in the case of serious underlying disease such as cardiopulmonary insuffi ciency, or in the case of anxiety regarding the endoscopy procedure, we must consider other screening methods of the upper GI series. Other screening methods for gastric cancer include the serum pepsinogen test and trefoil-3 test. In Korea, routine screening of gastric cancer is recommended for healthy adults aged 40 and older. A screening test interval has not been established, but approximately 2 to 3 years is recommended in normal patients, while more frequent testing is recommended in those at high risk for gastric cancer.
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KEYWORD
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Stomach Neoplasms, Early Detection of Cancer, Endoscopy, Upper Gastrointestinal Series, Pepsinogen A, Trefoil-3
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