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KMID : 1039620140040010049
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Korean Journal of Family Practice
2014 Volume.4 No. 1 p.49 ~ p.55
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The Relationships between Metabolic Syndrome with Liver Function Test, Pulmonary Function Test, White Blood Cell Count, and Ferritin: The Fifth Korean National Health and Nutrition Examination Survey 2010
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Lee Chae-Hun
Lee Ka-Young
Park Tae-Jin
Park Da-Jung
Lee Hyun-Joo
Jung Yong-Hyun
Kim Dong-Hyun
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Abstract
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Background: The aim of this study was to fi nd the relationship between metabolic syndrome (MetS) and liver function test
(LFT), pulmonary function test (PFT), white blood cell (WBC) count, and serum ferritin.
Methods: The data of 6,740 individuals (2,958 men and 3,782 women) aged 19 years or older from the fi fth Korea National
Health and Nutrition Examination Survey in 2010 were used. The relationship of MetS which was defi ned using the ATP III criteria, with serum γ-glutamyltranspeptidase (GGT), alanine aminotransferase (ALT), aspartate aminotransferase (AST), forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC), WBC, and ferritin were analyzed using complex sample descriptive and logistic regression analyses, analysis of covariance (ANCOVA), and receiver operating characteristic curves (ROC).
Results: The prevalence of MetS was 25.8% in men and 19.3% in women. When the model included age, education, alcohol consumption, cigarette smoking, physical activity, WBC, ferritin, AST, ALT, and GGT as independent variables, MetS was positively associated with WBC, ferritin, GGT, and ALT in men and with WBC and ALT in women. Although ANCOVA revealed an inverse relationship of MetS with FEV1 and FVC in men, these fi ndings were not replicated in women. In the ROC analyses, the sensitivity and specifi city of WBC, ferritin, LFT, and PFT for classifying MetS were respectively 36.2% to 69.2% and 46.5% to 72.3% in men and 59.8% to 75.7% and 50.7% to 67.1% in women.
Conclusion: Higher WBC, ferritin, GGT and ALT in men and higher WBC and ALT in women may suggest the presence of MetS.
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KEYWORD
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Metabolic Syndrome, Liver Function Tests, Leukocytes, Ferritins, Respiratory Function Tests
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