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KMID : 1039620140040020143
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Korean Journal of Family Practice
2014 Volume.4 No. 2 p.143 ~ p.148
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The Effects of Patients’ Sex, Age, and Nodule Size on the Malignancy Rate of Indeterminate Thyroid No
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Kim Tae-Young
Jang Hui-Jong
Kim Kyung-Chae
Choi Bong-Gyu
Lee Chang-Young
Choi Hye-Kyung
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Abstract
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Background: Thyroid nodules are very common clinically and their incidence has increased recently. This study is to determine the malignancy rate of indeterminate nodules and the effects of patient’s age, sex and nodule size.
Methods: Indeterminate nodules detected by ultrasonography between January 2010 and December 2012 were examined by sono-guided fi ne needle aspiration biopsy. We retrospectively evaluated the frequency of thyroid cancer using Fisher’s exact test and logistic regression.
Results: Of 212 indeterminate nodules in 143 patients, sono-guided fi ne needle aspiration biopsy was performed on 84. There were 6 inadequate nodules (7.1%), 53 hyperplastic nodules (63.1%), 6 thyroiditis (7.1%) and 19 thyroid cancers (22.6%). No signifi cant differences were found statistically between the malignancy rate of indeterminate nodules and age, sex, and nodule size.
Conclusion: The percentage of thyroid cancers among indeterminate nodules (22.6%) is about 4 times as high as that of general nodules. In the case of indeterminate nodules, sono-guided fi ne needle aspiration is highly recommended in all conditions-regardless of age, sex and nodule size-because of its low cost and high malignancy rate of thyroid nodules in Korea.
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KEYWORD
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Thyroid Nodule, Fine-Needle Aspiration, Thyroid Neoplasms
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