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KMID : 1039620150050030348
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Korean Journal of Family Practice
2015 Volume.5 No. 3 p.348 ~ p.353
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Factors Influencing Carotid Plaque Formation in Asymptomatic 50s Korean Men
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Cho Young-dae
Kye So-Shin
Lee Gyeong-In
Kim Jung-mee
Lee Ju-Hyun
Park Jung-hyun
Yoon Jea-kwang
Im Jung-youn
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Abstract
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Background : Atherosclerosis can cause adverse events such as cardiac ischemia, myocardial infarction, and stroke. Carotid plaque is a marker of atherosclerotic burden in adults and can be easily detected and examined by carotid ultrasonography. However, few reports on carotid plaques in the Korean population are available. In this study, we detected carotid plaques in asymptomatic Korean men and identified the factors that influence plaque formation.
Methods : Between April 2013 and May 2014, in total, 3,336 men in their 50s visited National Police Hospital for health check-ups. Among the eligible men, those who received treatment with anti-platelet agents (n=518) and those with a history of myocardial infarction or other cardiovascular diseases (n=355) were excluded. Finally, 2,463 subjects were enrolled. Clinical characteristics, results of laboratory examinations, and results of carotid artery ultrasonography were collected. Chi-square test and t-test were used to determine the relationship between each parameter of the data collected and the presence of carotid plaques. To identify the independent risk factors of carotid plaques, we performed multivariate logistic regression analyses.
Results : Among 2,463 asymptomatic men, 1,509 (61.3%) showed carotid plaques. Age, body mass index, waist circumference, systolic blood pressure, smoking history, fasting glucose levels, hemoglobin A1c levels, total cholesterol levels, low density lipoprotein cholesterol (LDLC) levels, and homocysteine levels differed among the study subjects according to the presence of carotid plaques. The results of the multivariate analysis showed that age, waist circumference, systolic blood pressure, smoking history, fasting glucose levels, LDLC levels, and homocysteine levels were the risk factors for carotid plaques (P<0.05).
Conclusion : Various factors were found to affect carotid plaque formation in Korean men in their 50s. We suggest that detection of carotid plaques is a useful method for the prediction of atherosclerosis.
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KEYWORD
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Carotid Artery Plaques, Ultrasonography, Atherosclerosis
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