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KMID : 1039620150050040441
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Korean Journal of Family Practice
2015 Volume.5 No. 4 p.441 ~ p.446
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Association between Vitamin D and Serum Cholesterol
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Choi Sung-Kyu
Park Jin-A
Hahm Sang-Keun
Yoon Ji-Young
Kim Sang-Min
Kim Jin-Young
Kim U-Tae
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Abstract
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Background : The prevalence of vitamin D insufficiency and deficiency is high all over the world. Many studies in other countries have reported that serum vitamin D levels are associated with serum cholesterol levels. This study focused on the relationship between vitamin D and cholesterol levels in middle-aged and elderly Korean adults.
Methods : We used data from 2,022 individuals (men 861, women 1,161), ranging in age from 50?69 years old, based on a sample from the Korea National Health and Nutrition Examination Survey V-3 in 2012. We then analyzed the relationship between serum 25-hydroxyvitamin D and serum total cholesterol (TC), triglyceride levels, high density lipoprotein cholesterol (HDLC), and low density lipoprotein cholesterol (LDLC). Vitamin D insufficiency was defined as less than 25-hydroxyvitamin D 20 ng/mL.
Results : Only triglyceride levels (P<0.001) were different between the vitamin D insufficiency group and the non-vitamin D insufficiency group. Serum 25(OH)D levels are significantly inversely correlated with serum triglyceride levels (r=-0.06, P=0.01). TC, HDLC, and LDLC are not different between the vitamin D insufficiency group and the non-vitamin D insufficiency group and are not significantly correlated with serum 25(OH)D levels.
Conclusion : Only triglyceride levels were higher in the vitamin D insufficiency group than in the non-vitamin D insufficiency group. Vitamin D is inversely correlated with TC and triglyceride levels. A standardized guideline for vitamin D insufficiency and deficiency should be established and further prospective studies should be performed on the correlation between vitamin D and cholesterol levels.
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KEYWORD
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Korea National Health and Nutrition Examination Survey, Vitamin D, Total Cholesterol, Triglyceride, Cholesterol, HDL, Cholesterol, LDL
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