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KMID : 1039620160060010014
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Korean Journal of Family Practice
2016 Volume.6 No. 1 p.14 ~ p.19
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Association between Vitamin D Levels and Metabolic Health in Adults with Type 2 Diabetes: The Korea National Health and Nutrition Examination Survey 2011?2012
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진로사:Jin Ro-Sa
정상아:Jung Sang-Ah/석상아:Sok Sang-Ah/이경나:Lee Kyung-Na/김선미:Kim Seon-Mee/한경도:Han Kyung-Do
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Abstract
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Background: Low levels of serum 25-hydroxy vitamin D (25(OH)D) have been associated with diabetes and metabolic syndrome. This study aimed to evaluate the association between 25(OH)D levels and metabolic health in Korean adults with type 2 diabetes.
Methods: We used data from 2011?2012 Korean National Health and Nutrition Examination Survey V. A total of 1,353 adults with type 2 diabetes were included. The association between metabolic health and type 2 diabetes was assessed by multivariate logistic regression analysis with adjustment for potential confounders.
Results: Serum 25(OH) levels were lower in diabetic patients with metabolically poor health than in diabetic patients with metabolically normal health. As the serum 25(OH)D level increased in the metabolically unhealthy group, waist circumference and triglyceride levels tended to significantly decrease. An inverse relationships was observed between 25(OH)D and the total number of components of metabolic syndrome (P=0.029). The adjusted odd ratios in the metabolically unhealthy group and the high triglyceride group, respectively, showed a decreasing tendency to have metabolic syndrome (P for trend = 0.013, 0.01, respectively).
Conclusion: Low serum 25(OH)D concentration is associated with poor metabolic health in diabetic adults in Korea, and is related to increased total triglycerides, which is a metabolic risk factor.
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KEYWORD
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Vitamin D, Metabolic Syndrome, Type 2 Diabetes
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