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KMID : 1039620160060030179
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Korean Journal of Family Practice
2016 Volume.6 No. 3 p.179 ~ p.184
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Bacterial Strains and Antimicrobial Resistance of Wound Infection in Burn Patients
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Yoon Jeong-Sook
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Abstract
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Background: The present study investigated the distribution of microbial species and antimicrobial resistance in burn wound infections.
Methods: The study participants consisted of 640 burn patients who were initially admitted to Bestian Seoul Hospital for burn infections between March 2012 and August 2014. Bacterial strains were identified via biochemical methods such as the API 20E/NE system (bioMerieux) and the VITEK microbial identification system (bioMerieux). Antimicrobial sensitivity was tested via the disc diffusion method and the VITEK 2 system (bioMerieux).
Results: The mean age of participants was 45.0±15.8 years and the male to female ratio was 4:1 (514/126). The mean total body surface area affected was 43%±19% (range, 5%?65%). The average first infection developed on the 14th±11th hospitalization day (range, 3?67 days), and the mean admission duration was 42±25 days (range, 3?98 days). The average microbial growth rate was 69.8%. The most commonly isolated infectious agent was Acinetobacter baumannii, which was identified in 37.2% of all growths. In addition, ninty two point one percent of A. baumannii infections were pandrug-resistant strains and also showed resistance to carbapenems. No colistin-resistant strains were observed. Other commonly isolated bacteria included methicillin-resistant Staphylococcus aureus (21%), Pseudomonas aeruginosa (17.8%), coagulase-negative S. aureus (13.9%), Enterococcus faecalis (5%), and Escherichia coli (3.9%). All observed strains of S. aureus were methicillin-resistant (100%).
Conclusion: Because there are many bacterial strains that are resistant to antimicrobials in burn patients, caution should be exercised during the a priori administration of antimicrobial treatments. The data from this study should serve as a guideline for treating wound infections in burn patients.
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KEYWORD
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Burn, Wound, Antimicrobial
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