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KMID : 1039620170070010060
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Korean Journal of Family Practice
2017 Volume.7 No. 1 p.60 ~ p.65
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Correlation between Hemoglobin A1c and Metabolic Syndrome in Adults without Diabetes under 60 Years of Age
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Kim Hong-Tae
Jo Jae-Bum
Jang Ji-Hyeong
Kang Jee-Hye
Seo Min
Keon Heug-Chun
Kim In-Seon
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Abstract
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Background: The occurrence of diabetic complications is likely to increase among adults with impaired glucose tolerance and impaired fasting glucose level with increasing blood glucose level. The aim of this study was to identify the correlation between glycated hemoglobin A1c level and metabolic syndrome, among non-diabetic adults.
Methods: The diagnosis of metabolic syndrome was based on the Cholesterol Education Program Adult Treatment Panel-III. The differences between increases in hemoglobin A1c and metabolic syndrome risk factors were analyzed by analysis of covariance. Multinomial logistic regression was used to investigate the correlation between hemoglobin A1c levels and the occurrence of metabolic syndrome.
Results: Increases in hemoglobin A1c levels were associated with significant increases in body mass index, rates of myocardial infarction, fasting blood glucose level, blood pressure, and total cholesterol levels, after adjusting for sex and age. Furthermore, the frequency of metabolic syndrome occurrence in the subjects with hemoglobin A1c level over 5.6% was 14 times higher than that of subjects with hemoglobin A1c level under 5.2%, the difference being statistically significant.
Conclusion: This study found a correlation between increases in hemoglobin A1c levels and occurrence of metabolic syndrome in non-diabetic adults. It is therefore important that adults without diabetes but with increased levels of hemoglobin A1c maintain adequate blood sugar control and are educated on healthy eating habits.
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KEYWORD
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Diabetes, Blood Sugar, Hemoglobin A1c, Metabolic Syndrome
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