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KMID : 1039620170070030348
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Korean Journal of Family Practice
2017 Volume.7 No. 3 p.348 ~ p.352
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Factors Affecting Mammographic Density in Korea Women Older Than 40 Years
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Lee Yeon-Hui
Han Min-Kyu
Lee Woo-Sung
Park Jin-Woo
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Abstract
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Background: A dense mammogram is a risk factor of breast cancer and is associated with decreased mammographic sensitivity and specificity. The purpose of this study was to evaluate several factors that influence mammographic density in Korean women. Furthermore, we considered the effectiveness of mammography as a screening method for breast cancer.
Methods: The study subjects were 3,013 women older than 40 years who underwent screening mammography between January 2, 2015, and October 31, 2015, at health promotion centers. We classified breast density patterns as either non-dense or dense by using the Breast Imaging Reporting and Data System (BI-RADS). Univariate and multivariate logistic regression models were used for the statistical analysis.
Results: In the univariate logistic regression, older age, higher body mass index, older age at menarche, and history of lactation were associated with more-fatty breasts. On the contrary, premenopausal status and use of hormone replacement therapy were associated with dense breasts. In the multivariate logistic regression, age and body mass index were inversely associated with breast density. Compared with the postmenopausal women, the premenopausal women had a 2.66-fold increase in breast density (odds ratio, 2.66; 95% confidence interval, 1.93?3.67).
Conclusion: Young age, lower body mass index, and premenopausal status were significantly associated with dense breasts in the Korean women in this study who were older than 40 years. Therefore, women with dense breasts who have the aforementioned risk factors need to be managed by individualized strategies with consideration of their age, breast obesity, and so on.
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KEYWORD
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Breast, Mammography, Mammographic Density, Women
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