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KMID : 1039620170070030442
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Korean Journal of Family Practice
2017 Volume.7 No. 3 p.442 ~ p.445
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Rates of Hepatitis B Surface Antibody Formation in Young Medical Volunteers Travelling to Foreign Countries and the Need to Vaccinate
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Choi Byung-Keun
Chung Do-Heun
Song Yun-Ah
Chung Su-Bin
Yoo Byung-Wook
Cho Yong-Jin
Oh Jung-Eun
Cho Choo-Yon
Hong Sung-Ho
Shin Kyung-Suk
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Abstract
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Background: Hepatitis B vaccination was first introduced in Korea in 1983, and was included in the routine infant immunization schedule in 1991. To date, no data are available on the extent of hepatitis B antibody formation after vaccination. Since medical volunteers are required to receive vaccination before traveling abroad for medical service, our study evaluated the effectiveness of hepatitis B vaccination in medical service volunteers travelling to foreign countries.
Methods: We surveyed 665 volunteers who underwent a general health check-up at the Department of Family Medicine before traveling abroad. We divided volunteers into three groups based on their year of birth (group 1, 1983?1988; group 2, 1989?1991; and group 3, 1992?present). Levels of antibodies to hepatitis B surface antigen (HBsAB, anti-HBs) were tested by performing chemiluminescent immunoassays.
Results: A total of 655 healthy individuals (188 males and 477 females) were screened. The percentage of participants who
tested positive for anti-HBs as 28.6% in group 1, 44.5% in group 2, and 58.1% in group 3. The overall trend showed an inverse association between age and anti-HBs formation.
Conclusion: In participants born after the inclusion of hepatitis B vaccination in the routine infant immunization schedule as part of national policy, the rate of anti-HBs formation increased to 58.1%, compared to 28.6% and 44.5% in participants born before 1990 and 1987, respectively. Therefore, a screening to confirm successful formation of hepatitis B antibodies should be performed for medical volunteers travelling to foreign countries. Volunteers with no antibodies against hepatitis B should consider receiving the vaccination.
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KEYWORD
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Hepatitis B Antibody, Vaccination of Hepatitis B, Booster of Hepatitis B, Antibody Formation of Hepatitis B
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