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KMID : 1039620170070060877
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Korean Journal of Family Practice
2017 Volume.7 No. 6 p.877 ~ p.884
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Coffee Consumption and Arterial Stiffness in Korean Adults
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Kim Seung-A
Sung Eun-Ju
Kim Cheol-Hwan
Shin Ho-Cheol
Chang Yoo-Soo
Jo Ji-Yeung
Lee Seung-Min
Kang Sae-Mi
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Abstract
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Background: Coffee is a popular beverage that is heavily consumed in Korea and worldwide. Studies on the associations between coffee consumption and arterial stiffness are rare in Korea. This study examined the possible association between coffee consumption and brachial-ankle pulse wave velocity (baPWV) as a subclinical atherosclerosis indicator in Korean adults.
Methods: We conducted a cross-sectional study of 22,005 Korean males and females aged 20?70 who completed a food frequency questionnaire and underwent a health checkup including measurement of baPWV between January 2013 and December 2015.
Results: Compared with <1 cup/day coffee consumption, the difference in baPWV was -3.61 (95% confidence interval [CI], -11.85?4.62) for the highest category (median, 5 cups per day), -7.89 (95% CI, -12.83?-2.59) for the second highest category (median, 3?5 cups per day), and -5.34 (95% CI, -9.44?-1.25) for the third highest category (median, 1?3 cups per day) in multivariate logistic regression analysis (Model 2, P for quadratic trend=0.008). Looking at separate outcomes, coffee consumption was nonlinearly associated with baPWV. However, this correlation was stronger in men than in women (P for quadratic trend=0.001 vs. 0.934, Model 2).
Conclusion: In a large sample, moderate coffee consumption was associated with lower arterial stiffness. However, the association between coffee consumption and arterial stiffness may differ between men and women. Further prospective or interventional studies are needed to confirm a causal association.
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KEYWORD
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Coffee, Arterial Stiffness, Cardiovascular Disease, Cross-Sectional Study
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