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KMID : 1039620170070060909
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Korean Journal of Family Practice
2017 Volume.7 No. 6 p.909 ~ p.914
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The Relationship between Triglyceride, Triglyceride to High Density Lipoprotein Cholesterol Ratio and Brachial Ankle Pulse Wave Velocity among Healthy Adults
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Youn Jae-Hyun
Jung Ji-Hoon
Kim Jung-Hyun
Kim Hyun-Woo
Cho Byung-Shik
Kim Sun-Whan
Jung Seung-Jin
Lee Dong-Won
Cho Sang-Hyun
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Abstract
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Background: This study investigated the correlation between triglyceride (TG) or the triglyceride to high density lipoprotein cholesterol (TG/HDL-C) ratio and the brachial ankle pulse wave velocity (baPWV), which is widely used as an indirect measure of atherosclerosis.
Methods: The study included 1,331 adults (721 men, 610 women) aged between 20 and 65 years with no underlying disease, who underwent baPWV measurement at a general health checkup between May and October 2015. Multiple linear stepwise regression analysis was performed for TG and the TG/HDL-C ratio, using the results of univariate correlation analysis between baPWV and body measurements and biochemical parameters as variables, in addition to age, alcohol use, and smoking history.
Results: There was a significant difference in baPWV according to sex (male>female), and a positive correlation was found between baPWV and TG or the TG/HDL-C ratio in univariate analysis. Regression analysis of TG or the TG/HDL-C ratio and baPWV, after correction by calibrating all variables, showed β=0.078 and P=0.046 for TG and β=0.1 and P=0.004 for the TG/HDL-C ratio for men. For women, β=0.124 and P<0.001 for TG and β=0.112 and P=0.001 for the TG/HDL-C ratio. The results showed a significant relationship in both men and women.
Conclusion: There was a significant relationship between TG or the TG/HDL-C ratio and baPWV after controlling for demographic factors in adults without underlying disease.
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KEYWORD
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Arterial Stiffness, Brachial Ankle Pulse Wave Velocity, Triglyceride, Triglyceride to High Density Lipoprotein Cholesterol Ratio
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