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KMID : 1039620170070060915
Korean Journal of Family Practice
2017 Volume.7 No. 6 p.915 ~ p.921
Effects of Pneumococcal and Influenza Vaccine in Elderly Inpatients
Cheon Seong-Hi

Kim Hye-In
Lee Keun-Mi
Jung Seung-Pil
Abstract
Background: Pneumococcal and influenza vaccination are effective in reducing morbidity and mortality. Our study investigated the effects of pneumococcal and influenza vaccination in elderly inpatients.

Methods: The medical records of 1,076 inpatients over 65 years old in the Department of Internal Medicine in Yeungnam University Medical Center (Deagu, Korea) between October 2015 and March 2016 were reviewed. Vaccination data were obtained from the Korea Centers for Disease Control and Prevention web system. The chi-square test was used to analyze univariate factors associated with pneumonia and mortality. To estimate probabilities of binary responses with vaccines as predictor variables, we performed logistic regressions for multivariate analyses after adjusting for confounding factors. The analyses were performed using IBM SPSS Statistics ver. 23.0. A P-value<0.05 was considered to indicate a significant difference between groups.

Results: Pneumococcal and influenza vaccination coverage rate were 73.4% and 77.2% respectively. There were statistical associations between pneumococcal conjugate vaccine and pneumonia in the group aged 75 years and over and pneumococcal conjugate vaccine and mortality in the total group. Influenza vaccination and mortality associated in the total group and the group aged 65?75 years. Pneumonia-associated morbidity was high with pneumococcal conjugate vaccine in the group aged 75 years and over; influenza vaccination decreased the incidence of pneumonia in the total group.

Conclusion: In elderly inpatients, the pneumococcal vaccination rate was high, but its effectiveness was uncertain. However, influenza vaccination had a positive effect in reducing pneumonia-associated morbidity.
KEYWORD
Pneumococcal Vaccines, Influenza Vaccines, Pneumonia, Mortality, Elderly
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