KMID : 1039620180080010047
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Korean Journal of Family Practice 2018 Volume.8 No. 1 p.47 ~ p.51
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The Effect of Colonoscopy on the Diagnosis of Impaired Fasting Glucose in Health Examination Subjects
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Kim Na-Rae
Im Jae-Seok Cho Yong-Jin Hong Sung-Ho Cho Choo-Yon Oh Jung-Eun Yoo Byung-Wook Shin Kyung-Suk Joe Hyun Shin Hwang-Sik Son Doo-Yong
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Abstract
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Background: Early diagnosis of impaired fasting glucose (IFG) is important because 15%?30% of IFG patients are known to progress to diabetes mellitus in 5 years. In this study, patients were classified into two groups as follows: patients who underwent colonoscopy and who did not. We compared fasting glucose and glycated hemoglobin A1c (HbA1c) levels between the two groups. The fasting glucose levels of the subjects from each group whose HbA1c levels were between 5.7% and 6.4% were identified to determine how colonoscopy affects their fasting glucose levels.
Methods: The physical assessments, fasting glucose levels, and HbA1c levels of 19,707 patients who visited a Health Promotion Center were examined, and the subjects were divided into 3 subgroups according to HbA1c level (¡Â5.6%, 5.7%?6.0%, and ¡Ã6.1%). Then, we compared fasting glucose levels between the colonoscopy and non-colonoscopy groups.
Results: The colonoscopy group showed a significant decrease in mean fasting glucose level in comparison with the non-colonoscopy group. The patients in the subgroups with HbA1c levels of ¡Â5.6% and 5.7%?6.0% who underwent colonoscopy presented significantly decreased fasting glucose levels. However, no significant difference was observed in the ¡Ã6.1% subgroup.
Conclusion: We confirmed that the two subgroups with HbA1c levels of ¡Â5.6% and 5.7%?6.0% tended to exhibit decreased fasting glucose levels by prolonged fasting time according to performing colonoscopy, failing to diagnose IFG precisely. Therefore, we recommend to examine the HbA1c level on the day performing colonoscopy or to measure the fasting glucose level on another day to diagnose IFG.
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KEYWORD
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Colonoscopy, Glycated Hemoglobin A1c, Health Promotion, Impaired Fasting Glucose
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