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KMID : 1039620180080040578
Korean Journal of Family Practice
2018 Volume.8 No. 4 p.578 ~ p.584
The Sex-Differential Relationship between Metabolic Syndrome and Health-Related Quality of Life in Non-Urban Residents
Kim In-Sub

Ko Hyeon-Young
Shin Su-Jeong
Sim Min-Seob
Song Hyoung-Gon
Song Yun-Mi
Abstract
Background: The relation between metabolic syndrome (MetS) and health-related quality of life (QOL) based on sex were controversial with few studies conducted in rural areas.

Methods: The study subjects were 966 residents (372 men and 594 women) of a Korean non-urban community, who undertook a routine medical check-up that was provided free of charge. We assessed the QOL using the EuroQoL-5 Dimensions (EQ-5D) and EuroQoL Visual Analog Scale (EQ-VAS).MetS was identified based on the modified National Cholesterol Education Program-Adult Treatment Panel III criteria. A multiple logistic regression analysis was performed to assess the odds ratio (OR) and 95% confidence interval (CI) for the risk of having low QOL in subjects with MetS, as compared to that in subjects without MetS.

Results: In both sexes, there were no significant differences in the mean levels of the QOL index or EQ-VAS between those with or without MetS. In women, MetS was associated with an increased risk of having a low EQ-5D index score (OR, 1.66; 95% CI, 1.12?2.47), whereas men with MetS tended to have a decreased risk of having a low EQ-5D index score (OR, 0.53; 95% CI, 0.30?0.94). There was no association between MetS and low EQ-VAS in both sexes.

Conclusion: MetS in adults living in rural areas was significantly associated with health-related QOL, with differential directions based on sex. The risk of having low QOL was only evident in women. These findings suggest that special attention is needed toward the QOL of women with MetS.
KEYWORD
Metabolic Syndrome, Health-Related Quality of Life, Koreans
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