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KMID : 1039620180080050684
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Korean Journal of Family Practice
2018 Volume.8 No. 5 p.684 ~ p.689
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The Relation of High-Sensitivity C-Reactive Protein with Metabolic Syndrome in Korean Adults: Based on the Korean Health and Nutrition Examination Survey, 2015
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Kim Sung-Kyum
Park Jin-A
Hahm Sang-Keun
Shin Min-Woo
Yu Eun-Hye
Sohn Yong-Ho
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Abstract
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Background: Metabolic syndrome is a group of multiple metabolic disorders that increase the risk of cardiovascular diseases and type 2 diabetes. C-reactive protein (CRP) level is a marker of systemic inflammation, and its correlation with coronary arterial disease has recently been highlighted. The purpose of this study was to determine the relationship between metabolic syndrome and CRP level, as well as between each metabolic syndrome component and CRP level.
Methods: On the basis of the data from the Sixth Korea National Health and Nutrition Examination Survey conducted in 2015, 3,705 people were selected. They were grouped according to general and lifestyle characteristics such as age, sex, alcohol drinking, and smoking status. The correlation of high-sensitivity (hs-CRP) level according to these variables was analyzed statistically. The correlation between each component of the metabolic syndrome and hs-CRP level was examined using one-way analysis of variance. Finally, the association of hs-CRP level with metabolic syndrome was examined using logistic regression analysis.
Results: hs-CRP level correlated with male sex, age, high-risk drinking, and smoking status. Overall, high hs-CRP level correlated with the high incidence rate of metabolic syndrome. The metabolic syndrome components such as waist circumference, triglyceride level, high-density lipoprotein cholesterol level, blood pressure, and blood glucose level showed statistically significant correlations with hs-CRP level.
Conclusion: Each metabolic syndrome component showed a significant difference according to hs-CRP level. The group with metabolic syndrome had a high hs-CRP level as a whole. This study showed that high hs-CRP levels were also associated with the prevalence of metabolic syndrome.
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KEYWORD
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Korea National Health and Nutrition Examination Survey, Metabolic Syndrome, High-Sensitivity C-Reactive Protein, Korean Adult
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