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KMID : 1039620180080050759
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Korean Journal of Family Practice
2018 Volume.8 No. 5 p.759 ~ p.763
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A Comparison of Tendency of Suicidal Ideation between the Groups that Begin Hormone Replacement Therapy before and after the Onset of Menopause: The Korean National Health and Nutrition Examination Survey IV from 2007-2009
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Park Se-Mi
Jung Yong-Hwa
Lee No-Jin
Bae Keun-Joo
Kim Ji-Hyun
Park Seok-Won
Cho Kyung-Hwan
Kim Yang-Hyun
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Abstract
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Background: Many women experience symptoms of menopause for which they are recommended hormone replacement therapy (HRT). However, no study has shown whether HRT administration before the onset of menopause aids mental status such as in cases of depression and suicidal ideation. Here, we investigated this issue.
Methods: We analyzed the data from the Korean National Health and Nutrition Examination Survey, 2007?2009. We included 180 postmenopausal women to whom HRT was administered. We studied the relationship between the point at which HRT was started and the mental status of the women using self-reported questionnaires.
Results: The tendency toward suicidal ideation was higher in the HRT before menopause onset than the HRT after menopause onset group (P＜0.05). After adjustment for underlying diseases, the odds ratio for suicidal ideation was 0.475 (0.190?1.190; P＜0.05) in the after group. The study had several limitations. We could not assess the difference in severity of menopausal symptoms between the before and after group. Suicidal ideation during the preceding 1 year was assessed; thus, we were unable to identify the participants who had previously recovered from suicidal ideation. An insufficient number of individuals were assessed with regards to depression and suicidal ideation.
Conclusion: When physicians recommend early HRT administration, they must pay attention to patient mental status. If they notice mental or mood problems, continuous close observation and proper intervention are needed.
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KEYWORD
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Hormone Replacement Therapy, Depression, Suicidal Ideation, Menopause
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