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KMID : 1039620180080060864
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Korean Journal of Family Practice
2018 Volume.8 No. 6 p.864 ~ p.869
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Seroprevalence Rate of Hepatitis A in Medical Personnel of the National Medical Center of Korea, 2013-2016
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Hwang Tae-Ho
Shin Eun-Ju
Kim Jae-Yoon
Kim Yeon-Jae
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Abstract
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Background: Korean adults are at high risk for hepatitis A because of a low seroprevalence rate in the population, especially in healthcare and medical professionals, among whom seroprevalence is highly critical for immunity. Thus, this study aimed to investigate the seroprevalence rate of hepatitis A among newly hired medical personnel and healthcare workers at the National Medical Center of Korea from 2013 to 2016.
Methods: Subjects were medical personnel and healthcare workers newly hired at the National Medical Center of Korea from January 1, 2013 to December 31, 2016. Serum samples were tested for immunoglobulin G antibodies against hepatitis A virus using a bead-based immunoserological assay, and nuclear medical testing (Cobra II Gamma Counter). Subjects’ medical records were retrospectively reviewed.
Results: Of the 563 total subjects, 189 (33.6%) were seropositive for hepatitis A, with a higher seroprevalence rate among omen (37.3%) than among men (26.9%). By age group, the seroprevalence rates among men were 11.5%, 23.3%, 77.8%, and 100% for patients 20?29, 30?39, 40?49, and ≥50 years old, respectively. Among women, the seroprevalence rates by age group were 18.8%, 35.5%, 85.1%, and 91.7% for patients 20?29, 30?39, 40?49, and ≥50 years old, respectively.
Conclusion: All medical personnel and healthcare workers in their 20s and 30s should be tested for anti-hepatitis A virus immunoglobulin G, and if the results are negative, active immunization should be considered for these individuals.
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KEYWORD
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Hepatitis A, Health Personnel, Hepatitis A Antibodies, Hepatitis A Vaccines
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