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KMID : 1039620190090010064
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Korean Journal of Family Practice
2019 Volume.9 No. 1 p.64 ~ p.70
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The Relationship between Serum C-Reactive Protein and the Coffee Consumption in the Korean Adult Men and Women
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Kim Youn-Jung
Lee Keun-Mi
Jung Seung-Pil
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Abstract
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Background: Coffee is a rich source of dietary antioxidants and is one of the most popular beverages worldwide. In recent times, substantial research has been published on its anti-oxidative and anti-inflammatory effect in addition to its effect as a stimulant. Chronic low-grade inflammation is known to affect the pathogenesis of diverse diseases such as cerebrovascular and cardiovascular disease, cancer, metabolic syndrome, type 2 diabetes mellitus, and obesity. Serum C-reactive protein (CRP) is a good marker of chronic inflammation in the body. Therefore, we examined the relationship between coffee consumption and serum CRP.
Methods: Participants were 759 men and 1,003 women, aged 20?64 years, who participated in the Korea National Health and Nutrition Examination Survey, 2015. We categorized coffee consumption as follows: less than one cup a day, two to four cups a day, and five or more cups a day. Additionally, we classified women into pre- and post-menopausal women. Multiple linear regression analyses were conducted to evaluate the relationship between coffee consumption and serum CRP.
Results: Coffee consumption showed no measurable relationship with serum CRP in men and in pre- and post-menopausal women. However, serum CRP increased progressively with increase in coffee consumption in men reported high-risk alcohol use (P=0.005).
Conclusion: Except for high-risk male drinkers, there is no association between coffee consumption and serum CRP.
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KEYWORD
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Caffeine, Coffee, C-Reactive Protein, Alcohols
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