KMID : 1039620200100060456
|
|
Korean Journal of Family Practice 2020 Volume.10 No. 6 p.456 ~ p.460
|
|
Relationship between Serum Vitamin E Level and Serum High-Sensitivity C-Reactive Protein in Koreans: Based on National Health and Nutrition Survey
|
|
Kim Jun-Tae
Kim Sun-Mi
|
|
Abstract
|
|
|
Background: Inflammation plays a major role in atherothrombosis, and measuring inflammatory markers such as high-sensitivity C-reactive protein (hs-CRP) may provide a novel method for identifying individuals at high risk of plaque rupture. Atherogenesis results from the oxidation of lipids in low-density lipoprotein (LDL). Vitamin E facilitates the reduction in LDL-oxidation, and increases the antioxidant defense system. Therefore, our study aimed to examine the relationship between vitamin E and hs-CRP levels in Korean adults.
Methods: We used data from the Seventh Korea National Health and Nutrition Examination Survey (2016?2018). The study population included healthy adults aged >20 years. We investigated age, blood pressure, glucose levels, total cholesterol, triglyceride, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, body mass index, serum vitamin E, and serum hs-CRP levels. We analyzed the relationship between serum vitamin E and serum hs-CRP levels using multiple regression tests.
Results: On statistical analysis, vitamin E levels showed a positive correlation with hs-CRP levels in the female group and the total of the unadjusted model. However, the R2 value is low. After adjustment for factors that may affect hs-CRP, no significant correlation was observed between serum vitamin E and serum hs-CRP levels.
Conclusion: No significant correlation was observed between serum vitamin E and serum hs-CRP levels. Further research is needed on this topic.
|
|
KEYWORD
|
|
Vitamin E, High-Sensitivity C-Reactive Protein, Cardiovascular Disease, Antioxidant
|
|
FullTexts / Linksout information
|
|
|
|
Listed journal information
|
|
|
|