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KMID : 1129720000170010081
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Korean Journal of Acupuncture
2000 Volume.17 No. 1 p.81 ~ p.100
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Central Localization of the Neurons Projecting to the Urinary Bladder Meridian
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Kim Jeong-Yeon
Jun Hong-Jae
Lee Sang-Ryoung
Lee Chang-Hyun
Chung Ok-Bong
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Abstract
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The existence of meridians is supported by various studies of their biophysical characteristics. Low electrical resistance of the skin was reported along the path of meridians1). Meridian acupoints were concentration sites of neural structure, subcutaneous nerve and nerve plexus2,3). The location of meridian points correspond to trigger point and motor point4) and, more recently, investigators were able to demonstrate meridians using a variety of biophysical methods, including electricity, heat, and radioactive isotopes5,6,7). The majority of these results were concerned with blood vessels, lymphatics and nerve in epidermis, dermis, subcutaneous tissue, fascia and muscles under the meridian acupoints. Plummer3) proposed that the nature of acupuncture loci is actually two holes, one in the dermis due to a neurovascular bundle or nerve piercing it, and directly beneath it in the deep fascia due to a perforating vein, neurovascular bundle or nerve piercing it. These holes are correspondant to the greater passage of biological electrical current from deeper tissues to the surface of body and autonomic nerve at these points may be involved in monitoring this current for purposes of homeostasis. These results suggest partly or completely concerned with nervous system. In the past, studies on the organization of innervation of the peripheral viscera have utilized degeneration methods, retrograde transganglionic tracers, HRP8), true blue9), fast blue10) and cholera toxin b subunit(CTB)11) injected into peripheral organs and tissues, and applied directly to cut nerves. Electrophysiological methods were used for investigation motor function of peripheral organs after stimulations. but these experiments were limited for identification of chains of central neurons innervating a specific organs because of transganglionic tracer12,13). A recent retrograde tracer used in neuroanatomical tracing techniques involving herpes viruses, were used to investigation of neural pathways of peripheral organs and tissue. These viruses can across synapses and have the potential to reveal pathways which connect various peripheral tissue, muscle and glands to central nervous system(CNS)14). Most investigators using pseudorabies virus, Bartha strain(PRV-Ba), for neuroanatomical studies. These weakend strains of PRV-Ba has been shown to be a specific retrograde transneuronal markers15). The present morphological study examines location of CNS neurons and neural pathways innervate the urinary bladder, UB28, UB40 and Ren3, and investigated the viscera-meridian-meridian point relationship.
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KEYWORD
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足太陽膀胱經(Urinary bladder meridian), 膀胱(Urinary bladder), 膀胱兪(BL28), 委中(BL40), 中極(CV3), Pseudorabies virus, 中樞神經系(Central nervous system)
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FullTexts / Linksout information
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