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KMID : 1129720010180020037
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Korean Journal of Acupuncture
2001 Volume.18 No. 2 p.37 ~ p.46
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The Effect of Lilii Bulbus on Anti-cancer and Immunocytes
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Kang Duk-Su
Kim Ho-Keun
Jung Jong-Sun
Lee Yun-Suk
Sun Sung-Kyu
Han Jong-Hyun
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Abstract
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The effect of Lilii Bulbus on the human cancer cell-lines(A431 and KHOS-NP), the regulation of immune cells and the apoptosis, nitric oxide(NO) from macrophage in mice were studied. Lilii Bulbus decreased the proliferation of human cancer cell lines(A431 and KHOS-NP), and inhibited proliferation of splenocytes in mice. Lilii Bulbus decreased production of NO from macrophages in vitro and vivo. Apoptosis was increased by Lilii Bulbus in a dose dependent manner.
Lilii Bulbus increased CD4+ TH cell however did not change CD8 Tc/Ts cell sub-population in the thymocytes of mice.
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KEYWORD
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Lilii Bulbus, Apoptosis, Human cancer cell-lines(A431 and KHOS-NP)
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