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KMID : 1129720030200010045
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Korean Journal of Acupuncture
2003 Volume.20 No. 1 p.45 ~ p.55
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The Scavenging Effect on NO, DPPH and Inhibitory Effect on IL-4 in Schizandrae Fructus Herbal-Acupuncture Solution
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Cho Hyun-Yeul
Yoon Jong-Seok
Seo Bo-Myung
Lee Sea-Youn
Kim Sung-Woong
Baek Jung-Han
Park Chi-Sang
Seo Jung-Chul
Han Sang-Won
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Abstract
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Backgrounds: It has been investigated about ageing theory. However, ageing mechanism still remains to be unknown. Since Harman proposes that ageing and ageing related diseases might be due to oxidative damage and these are modifiable by genetic and environmental factors. For designing an optimal nutritional countermeasure against ageing and ageing related disease, it is necessary to understand the ageing mechanism and other reactive species.
Objectives: Schizandra Chinesis has been clinically used to treat brain disease, respiratory or inflammatory disease etc. in Oriental medicine. The purpose of this study is to investigate the scavenging effect of Schizandrae Fructus herbal-acupuncture solution(SFHA) on NO, DPPH and IL-4.
Results: The results are summarized as follows; ① There is a significant scavenging effect of SFHA on NO in 0.1, 1, 10㎎/㎖ group after 24hrs. ② There is a significant scavenging effect of SFHA on DPPH in 1, 10㎍/㎖ group.
③ There is a significant inhibitory effect of SFHA on IL-4 in 1, 10, 100㎍/㎖ group.
Conclusions: These findings indicate that SFHA can be used as antioxidant or antiimflammatory drug. But further study is needed about the effect of SFHA.
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KEYWORD
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Schizandrae Fructus., Herbal-acupuncture, NO, DPPH, IL-4
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