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KMID : 1129720030200030101
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Korean Journal of Acupuncture
2003 Volume.20 No. 3 p.101 ~ p.114
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Immune response improvement induced by Herbal-acupuncture with Aucklandiae Radix infusion solution into Zusanli(ST36)
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Ahn Byeong-Soo
Lee Byung-Ryul
Yim Yun-Kyoung
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Abstract
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To study the effects of anti-cancer, anti-metastasis and immune response improvement of herbal-acupuncture with Aucklandiae Radix diffusae herba infusion solution(AKL-HAS), we injected AKL-HAS into Zusanli(St36) of C57BL/6 mice implanted intravenously with B16-F10 melanoma. The results were obtained as follows : 1. In the experiment groups treated with Aucklandiae Radix(AKL) Herbal-Acupuncture, the spleen cell proliferation in Balb/c mouse was significantly increased compared with that of the control group. 2. In the experiment groups treated with Aucklandiae Radix(AKL) Herbal-Acupuncture, the percentage of CD25+/CD4+, CD8+/CD3e+, CD69+/B220+, NK1.1+/CD3e+ cells in C57BL/6 mouse PBMCs was increased compared with that of the control group. 3. In the experiment groups treated with Aucklandiae Radix(AKL) Herbal-Acupuncture, the pulmonary colony number of C57BL/6 mice implanted intravenously with B16-F10 melanoma was decreased significantly compared with that of the control group. 4. In the experiment groups treated with Aucklandiae Radix(AKL) Herbal-Acupuncture, MST(Median Survial Time) and ILS(Increase of Life Span) of C57BL/6 mice implanted intravenously with B16-F10 melanoma were increased significantly compared with those of the control group.
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KEYWORD
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Aucklandiae Radix(AKL), Herbal-Acupuncture, Zusanli(St36), anti-cancer, immune response improvement
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