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KMID : 1129720030200030115
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Korean Journal of Acupuncture
2003 Volume.20 No. 3 p.115 ~ p.128
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Influence on the Anti-cancer and Immune response improvement of Herbal-acupuncture with Evodiae Fructus infusion solution into Zusanli(ST36)
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Park Ki-Hong
Lee Byung-Ryul
Yim Yun-Kyoung
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Abstract
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Objectives and methods : Study the anti-cancer, anti-metastasis and immune response improve- ment effects of Herbal-acupuncture with Evodiae Fructus infusion solution, we injected Evodiae Fructus infusion solution into Zusanli(St36) of C57BL/6 mouse which is corresponding to human Zusanli(St36). We observed its effect on the number of CD25+/CD4+, CD8+/CD3e+, CD69+/B220+, NK1.1+/CD3e+ cells in mouse PBMCs, the number of the pulmonary colony , MST and ILS of C57BL/6 mice implanted intravenously with B16-F10 melanoma.
Results and Conclusions : The spleen cells proliferation of the sample groups treated with EDR-HAS extract has increased significantly compared with that of the control group. The percentage of the CD25+/CD4+, CD8+/CD3e+, CD69+/B220+, NK1.1+/CD3e+ cells in C57BL/6 mouse PBMCs of the sample groups treated with EDR herbal-acupuncture has increased compared with that of the control group. The lung colony number of the sample groups treated with EDR herbal-acupuncture has decreased significantly compared with that of the control group. MST and ILS of the sample groups treated with EDR herbal-acupuncture have increased significantly compared with those of the control group.
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KEYWORD
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Evodiae Fructus(EDR), Herbal-Acupuncture, Zusanli(St36), anti-cancer, immune response improvement
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