KMID : 1129720040210030097
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Korean Journal of Acupuncture 2004 Volume.21 No. 3 p.97 ~ p.104
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Effect of Saururus chinensis (Lour.) Baill. Aquacupuncture on Anaphlylaxis in Mice
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Choi Kyu-Jung
Lee So-Young Kang Kyung-Hwa Lee Yong-Tae Song Chun-Ho
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Abstract
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Objective : We investigated the effect of Saururus chinensis (Lour.) Baill. aquacupuncture (SCB) on anaphylaxis in mice.
Methods : We conformed compound 48/80-induced mesenteric mast cell degranulation, active systemic anaphylatic shock and histamine release. Also observed acetic acid-induced vascular permeability and anti-dinitrophenyl (DNP) IgE-mediated passive cutaneous anaphylaxis.
Results : SCB inhibited mesenteric mast cell degranulation and active systemic anaphylatic shock induced by compound 48/80 dose-dependently. When SCB was pretreated by intra-peritoneal injection, the serum histamine levels were reduced. SCB also significantly inhibited acetic acid-induced vascular permeability. In addition, SCB showed a significant inhibitory effect on anti-dinitrophenyl (DNP) IgE-mediated passive cutaneous anaphylaxis.
Conclusion : These results indicated that SCB inhibits anaphylatic reaction.
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KEYWORD
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Saururus chinensis (Lour.) Baill. aquacupuncture, Anaphylaxis, Active systemic anaphylatic shock, Passive cutaneous anaphylaxis
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