|
KMID : 1129720050220010023
|
|
Korean Journal of Acupuncture
2005 Volume.22 No. 1 p.23 ~ p.32
|
|
|
Effect of Ephedrae Herbal Acupuncture Solution(EHS) on the Release of Thymus and Activation-Regulated Chemokine (TARC) in Human Bronchial Epithelial Cell
|
|
Chou Yu-Shih
Seo Jung-Chul
Lim Seong-Chul
Jung Tae-Young
Han Sang-Won
|
|
|
Abstract
|
|
|
Chemokines are important for the recruitment of leukocytes, which is essential in host defense to the sites of infection. The thymus and activation-regulated chemokine (TARC) is a CC chemokine which potentially plays a role via a paracrine mechanism in the development of allergic respiratory diseases.
Objectives : The objective of this study is to investigate the effect of Ephedrae Herba Herbal Acupuncture Solution(EHS) on the secretion of TARC of human bronchial epithelial cell.
Methods : Enzyme-linked immunosorbent assay (ELISA) was performed to detect the secretion of TARC. The cytotoxicity was measured by MTT assay.
Results : EHS significantly inhibited the secretion of TARC with a dose-dependant manner. The effective dosage did not have the cytotoxicity on human bronchial epithelial cell.
Conclusion : Results of our study imply that EHS would play an important role in modulation of TARC in human bronchial epithelial cells by MTT assay
|
|
|
KEYWORD
|
|
|
Ephedrae Herba Herbal Acupuncture Solution(EHS), thymus and activation-regulated chemokine (TARC), Human bronchial epithelial cells, A549
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|