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KMID : 1129720050220020043
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Korean Journal of Acupuncture
2005 Volume.22 No. 2 p.43 ~ p.56
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A Study on the Protective Mechanism of Moxi-tar on Cytotoxicity Induced by H202 in C6-glioma
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Ahn Seong-Hun
Ahn Young-Nam
Baek Tae-Bong
Song Moon-Young
Kim Kyung-Sik
Sohn In-Chul
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Abstract
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Objective : This study was produced to examine the effects of moxibustion that had been played important role to traditional oriental medical treatment on disease. Recently, it was reported that moxi-tar which is generated in the process of moxibustion as burning combustibles decreased NO and iNOS generation in and RAW 264.7 cells in our lab. The purpose of this research was to investigate the protect reaction on cell injury induced by the in cells.
Methods : cells were cultured in RPMI 1640 with FBS 10% in incubator. To study the protective effects of moxi-tar, we observed cell viability, DPPH activity, SOD activity, catalase activity and cell morphology after injury with .
Results : Moxi-tar increased cell viability about twice as much as that of being injury by (moxi-tar , ). And the results of free radical scavenger activity (), SOD activity and catalase activity (: 21.6 unit/ mg protein) were increased by moxi- tar as dose-dependent manner.
Conclusion : we concluded that the effects of moxibustion which is played important role in Oriental medicine, might be free radical scavenger effects induced by moxi-tar.
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KEYWORD
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Moxi-tar, cytotoxicity
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