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KMID : 1129720050220030105
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Korean Journal of Acupuncture
2005 Volume.22 No. 3 p.105 ~ p.117
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Effect of Juglandis Semen Herbal Acupuncture on Rat by Glycerol-Induced Acute Renal Failure
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Jung Hyun-Chol
Kim Cheol-Hong
Youn Hyoun-Min
Jang Kyung-Jeon
Ahn Chang-Beohm
Song Chun-Ho
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Abstract
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Objective : This study was undertaken to determine if Juglandis Semen herbal acupuncture(Ja) has a protective effect against glycerol-induced acute renal failure in rats.
Methods : Rats were dehydrated for 24hr and then injected with 5 ml/kg of 50 % glycerol, one-half of dose in each hindlimb muscle. In experiments for Ja effect, rats received 0.1 ml of Ja extraction in both sides of corresponding of human body and non-acupuncture points(the root of tail) for 3 days after injection of glycerol. The experimental group were divided into the Normal group, the Control group, the Ja to group(Ja-AS), the Ja to non-acupuncture points group(Ja-AN).
Results : There were significant decrease of urine volume, BUN, fractional glucose excretion, fractional phosphate excretion, total protein level in Ja-AS as compared with the control group.
Conclusion : This suggests that Ja-AS could be used in prevention and treatment of acute renal failure. However, the precise mechanisms of Ja protection remain to be determined.
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KEYWORD
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Juglandis Semen, Herbal acupuncture, Acute renal failure
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