|
KMID : 1129720050220040117
|
|
Korean Journal of Acupuncture
2005 Volume.22 No. 4 p.117 ~ p.127
|
|
|
The Effect of Plantaginis Semen Herbal Acupuncture on Acute Renal Failure in Rat
|
|
Cho Si-Young
Kim Cheol-Hong
Youn Hyoun-Min
Jang Kyung-Jeon
Ahn Chang-Beohm
Song Chun-Ho
|
|
|
Abstract
|
|
|
Objective : This study was undertaken to determine if Plantaginis Semen herbal acupuncture(PSA) has a protective effect on glycerol-induced acute renal failure in rats.
Methods : Rats were dehydrated for 24hr and then injected with 4 ml/kg of 50% glycerol in each hindlimb muscle. In experiments for PSA effect, rats were received 0.1 ml of PSA extraction in both sides of corresponding of human body for 3 days after injection of glycerol. The experimental group were divided into the normal group, the control group, the sample 1,2,3 group.
Results : Glycerol injection decreased glomerular filtration rate and increased urine volume, serum creatinine, BUN level and fractional excretion of . These results show that glycerol injection bring about acute renal failure. PSA significantly increased glomerular filtration rate and significantly decreased serum creatinine, BUN level and fractional excretion of as compared with control group.
Conclusion : These results suggest that PSA can be used in prevention and treatment for acute renal failure. However, the precise mechanisms of PSA protection remain to be determined.
|
|
|
KEYWORD
|
|
|
Plantaginis Semen, Herbal acupuncture, acute renal failure
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|