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KMID : 1129720060230010037
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Korean Journal of Acupuncture
2006 Volume.23 No. 1 p.37 ~ p.44
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Effects of Poncirus trifoliata Pharmacopuncture on plasma lipid composition and concentration of and IL-6 in rats fed high fat diet
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Lee Joon-Moo
Lee Jong-Wook
Lee Ji-Hyang
Lee Eun
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Abstract
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Objective : To investigate the effects of Poncirus trifoliata Pharmacopuncture on lowering lipid and contents of serum tumor necrosis and interleukin-6 (IL-6) in hyperlipidemic rats.
Methods : Triglyceride, total cholesterol, , and IL-6 levels in Poncirus trifoliata Pharmacopuncture groups were compared with those in the control group.
Results : Concentration of triglyceride and total cholesterol in plasma was decreased in the Poncirus trifoliata Pharmacopuncture groups. In Poncirus trifoliata Pharmacopuncre groups, plasma LDL-cholesterol showed a lower value and HDL-cholesterol showed a higher value than those of the control group. Contents of was decreased in the Poncirus trifoliata Pharmacopuncture groups. Contents of IL-6, however, were not significantly different.
Conclusions : The results suggest that Poncirus trifoliata Pharmacopuncture may have an impact on lipid metabolism to potentially prevent development of diabetes mellitus and accompanying cerebrovascular diseases.
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KEYWORD
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Poncirus trifoliata, Cholesterol, Triglyceride, Tumor necrosis, Interleukin-6
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