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KMID : 1129720060230020137
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Korean Journal of Acupuncture
2006 Volume.23 No. 2 p.137 ~ p.154
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The Effects of Herbal-acupuncture with Aconiti Iateralis Preparata Radix solutionon Collagen-induced arthritis
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Kim Yoon-Hee
Yim Yun-Kyoung
Lee Hyun
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Abstract
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Results: 1. In the AlPR-HA group, the incidence of arthritis and arthritis index were significantly decreased. 2. In the AlPR-HA group, the levels of in serum of the CIA mouse were significantly decreased. 3. In the AlPR-HA group, the levels of in spleen cell culture of the CIA mouse were significantly decreased. 4. In the Hematoxylin and eosin stain, the cartilage destruction and synovial cell proliferation were decreased in the AIPR-HA group. 5. In the Masson’s trichrome stain, the collagen fiber expressions were similar with that of the Normal group. 6. In the AlPR-HA group, the expression ratio of to cell and to cell were similarly maintained as Normal group in the CIA mouse lymph nodes. 7. In the AlPR-HA group, cells in the CIA mouse joint and cells and cells in the CIA mouse lymph nodes were significantly decreased. 8. In the AIPR-HA group, cells were significantly decreased in the CIA mouse spleen cell and were similarly maintained as Normal group in the CIA mouse lymph nodes.
Conclusions: These results suggest that AlPR-HA at 51’36 has an effect to control synovial cell proliferation and cartilage destruction in rheumatoid arthritis.
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KEYWORD
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Aconiti iateralis preparata radix, Herbal-Acupuncture, ST36, Collagen-induced arthritis (CIA), Rheumatoid arthritis (RA)
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