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KMID : 1129720060230040147
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Korean Journal of Acupuncture
2006 Volume.23 No. 4 p.147 ~ p.156
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Effects of Ginseng Radix herbal acupuncture on TNBS-induced colitis in rats
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Kim Jong-Sung
Chun Sang-Woo
Park Sang-Yeon
Park Sung-Ik
Kim Kyung-Sik
Kim Jae-Hyo
Koo Sung-Tae
Sohn In-Chul
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Abstract
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Objectives : The purpose of the present study is to evaluate the effects of herbal acupuncture with Ginseng Radix for the treatment to intestinal disease in the rat with 2, 4, 6-trinitrobenzenesulfonic acid (TNBS) induced colitis.
Methods : All animals were subjected to the injection of saline for a study control or TNBS into the lumen of the colon, 8cm proximal to the anus through the intestine. Ginseng Radix herbal acupuncture () were injected to the both acupoints at 2nd injection of TNBS in rats. Thus, the body weight, RBC count, WBC count, total protein, IgG levels and IgM levels were observed to study the effects of Ginseng Radix herbal acupuncture.
Results : Ginseng Radix herbal acupuncture on for TNBS-induced colitis inhibited the body weight loss rate but did not affect RBC and WBC counts. Furthermore, it inhibited the reduction of total protein concentration and serum IgG and IgM levels in TNBS induced colitis were recovered.
Conclusions : Herbal acupuncture with Ginseng Radix helps recover the TNBS-induced colonic damage and may be an important method for treatment of the colitis.
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KEYWORD
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colitis, Ginseng, Radix, herbal acupuncture
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