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KMID : 1129720080250010139
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Korean Journal of Acupuncture
2008 Volume.25 No. 1 p.139 ~ p.154
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Anti-oxidative effect of electroacupuncture to Yinlingquan (SP9) in AAPH induced oxidative stress of rats
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Lee Jung-Tae
Kim Young-Il
Yim Yun-Kyoung
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Abstract
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Objectives & Methods: The purpose of this study is to observe the anti-oxidative effects of electroacupuncture to Yinlingquan(SP9) in AAPH induced oxidative stress of rats. The author performed several experimental items including measurements of body weight, levels of albumin, total bilirubin, LDL-cholesterol, GOT and GPT in serum, levels of SOD, glutathione, catalase, NO and MDA in liver, histological analysis of liver. The conclusions are as follows.
Results: 1. In the SP9-EA group, the level of LDL-cholesterol was significantly decreased in comparison with that of the holder group and control group. 2. In the SP9-EA group, SOD activity, glutathione concentration in liver were increased, and NO concentration was decreased significantly in comparison with those of the control group and the holder group. 3. In the SP9-EA group, the density of liver tissue was maintained more similarly to the normal group in comparison with those of the control group and the holder group. 5. The results of the SP9-NR group showed similar tendencies with those of the SP9-EA group, but the effects were lower than those of the SP9-EA group.
Conclusion: These results suggest that electroacupuncture at SP9 has an anti oxidative effect through suppressing both the reduction of anti-oxidative enzymes and production of oxidized substances.
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KEYWORD
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anti-oxidativeeffect, Yinlingquan(SP9), electroacupuncture
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