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KMID : 1129720080250010197
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Korean Journal of Acupuncture
2008 Volume.25 No. 1 p.197 ~ p.211
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Study on anti-allergic effects of Arctii Fructus herbal acupuncture
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Jang Seok-Chang
Song Chun-Ho
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Abstract
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Objectives: We studied on anti-allergic effects of Arctii Fructus Herbal Acupuncture(AFHA) and Arctii Fructus Herbal Acupuncture Solution(AF).
Methods: In vivo, Animals were herbal-acupunctured AFHA at both ST36 three times for 5 days. Then, we investigated compound 48/80-induced active systemic anaphylaxis(ASA) using ICR mice and anti-DNP IgE-induced passive cutaneous anaphylaxis(PCA) using Sprague Dawley rat. In vitro, we measured cell viability, b-hexosaminidase, IL-4 and TNF-a release from RBL-2H3 cells after treatment of AF of various concentrations.
Results: In vivo, AFHA pretreatments at both ST36 inhibited compound 48/80-induced ASA. PCA was inhibited by AFHA pretreatments at both ST36. In vitro, AF treatments were not affect on cell viability and inhibited b-hexosaminidase, IL-4 and TNF-a release.
Conclusions: These results suggest that AFHA and AF may be beneficial in the inhibition of allergic inflammatory response.
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KEYWORD
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anti-allergiceffect, ArctiiFructus, herbalacupuncture
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