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KMID : 1129720080250030097
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Korean Journal of Acupuncture
2008 Volume.25 No. 3 p.97 ~ p.115
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Effects of Herbal-Acupuncture with Cistanches Herba Extract at KI10 (Eumgok) on Osteoporosis in Ovariectomized Mice
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Jeung Neon-Sik
Lee Byung-Ryul
Koo Sung-Tae
Yim Yun-Kyoung
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Abstract
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Objective & Methods: This study aimed to evaluate the effects of Cistanches Herba herbal-acupuncture
(CH-HA) at KI10 (Umgok) on osteoporosis induced by ovariectomy in mice. The results were as follows;
Results: CH-HA at KI10 significantly inhibited the overgrowth of tibia, the elevation of serum osteocalcin level, the reduction of tibial Ca and P level, the increase of tibial osteoclast like cells, the reduction of tibial TBV (trabecular bone volume), the overgrowth of tibial GPL (growth plate length) in ovariectomized mice. NP at KI10 significantly inhibited the reduction of BMD (bone mineral density) in ovariectomized mice, but CH-HA did not.
Conclusion: Taken together, CH-HA at KI10 has a protective or therapeutic effect for osteoporosis in ovariectomized mice. Therefore, it is suggested that CH-HA may be an useful therapeutics in clinical filed after further researches.
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KEYWORD
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Osteoporosis, Herbal-acupuncture, Cistanches Herba, KI10 (Umgok)
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