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KMID : 1129720090260020061
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Korean Journal of Acupuncture
2009 Volume.26 No. 2 p.61 ~ p.74
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Effects of High Frequency Warm Needling of LI4 Acupoint on the Carrageenan-induced Arthritis in Rats
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Park Sang-Yeon
Kwon Oh-Sang
Choi Won-Jong
Kim Jae-Hyo
Kim Kyung-Sik
Sohn In-Chul
Ahn Seong-Hun
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Abstract
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Objectives: The warm needling technique is a method which combines the effects of acupuncture with those of moxibustion. The purpose of this study was to find the stimulus effects of a high frequency warm needling device when stimulating acupoint LI4 on the carrageenan-induced arthritis.
Methods: This study was to observe the effects to edema reaction, WBF(weight bearing force), NO concentration, nNOS expression after the electro high frequency stimulus of high frequency warm needling device on LI4 with insulated acupuncture needle.
Results: The effect of the high frequency warm needling device is to rise up the temperature in proportion to the current intensity. After stimulating on the acupoint LI4 of the carrageenan-induced arthritis in rats with the high frequency warm needling device, it significantly reduced edema in the rat’s foot. In addition, WBF, NO concentration of spinal cord (n㏖/㎎), and nNOS relative expression were reduced.
Conclusions: The above results support the idea that stimulus by the high frequency warm needling device on LI4 produces a potent analgesic effect in the arthritis pain model of the rat. Moreover, stimulus by the high frequency warm needling device modulates endogenous NO through the suppression of nNOS protein expression.
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KEYWORD
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high frequency warm needling, acupuncture, carrageenan induced arthritis.
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