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KMID : 1129720100270010107
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Korean Journal of Acupuncture
2010 Volume.27 No. 1 p.107 ~ p.123
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A Study on the Effect of Herbal-acupuncture with Artemisiae Capillaris Herba at GB34 on Hyperlipidemia in Rat
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Lee Jung-Tae
Lee Byung-Ryul
Yang Gi-Young
Lee Hyun
Yim Yun-Kyoung
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Abstract
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Objective & Methods: The purpose of this study is to investigate the effects of Artemisiae Capillaris Herba herbal-acupuncture (ACH-HA) at GB34 (Yangleungchean) on hyperlipidemia induced with alloxan injection and high fat diet in rats. The author performed several experimental items to analyze the levels of various components and enzymes in serum, liver, as well as the histological changes of liver and aorta.
Results: 1. ACH-HA solution increased the DPPH radical scavenging activity in rat liver cells. 2. ACH-HA at GB34 significantly decreased the levels of serum total cholesterol, low-density lipoprotein (LDL)-cholesterol, free cholesterol and atherogenic index (AI), while significantly increased the ratios of high-density lipoprotein (HDL)/total cholesterol and phospholipid/total cholesterol in hyperlipidemic rats. 3. ACH-HA at GB34 significantly decreased serum aspartate aminotransferase (AST) level in hyperlipidemic rats. 4. ACH-HA at GB34 significantly increased hepatic glutathione (GSH) activity in hyperlipidemic rats.
Conclusion: From the above results, it is suggested that ACH-HA at GB34 may have therapeutic and preventive effects on hyperlipidemia.
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KEYWORD
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Hyperlipidemia, Herbal-acupuncture, ACH(Artemisiae Capillaris Herba), GB34(Yangleungchean)
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