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KMID : 1129720100270030025
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Korean Journal of Acupuncture
2010 Volume.27 No. 3 p.25 ~ p.46
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The Effect of Achyranthis Radix Herbal-acupuncture on Hyperlipidemia in Rats
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Choi Joon-Soo
Yim Yun-Kyoung
Lee Byung-Ryul
Yang Gi-Young
Kim Jae-Kyu
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Abstract
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Objective & Methods : The purpose of this study is to observe the effects of herbal- acupuncture with Achyranthis Radix(AR-HA) at GB34(Yangleungchean) on hyperlipidemia in rats. The author performed several experimental items to analyze the levels of various components and enzymes in serum and liver, as well as the histological changes of liver and aorta.
Results : 1. Achyranthis Radix herbal acupuncture solution increased DPPH radical scavenging activity and HMG-CoA reductase inhibition rate in rat liver cells. 2. AR-HA at GB34 decreased the level of serum total cholesterol, and increased the ratios of HDL-cholesterol to total cholesterol, phospholipid to total cholesterol in hyperlipidemic rat. 3. AR-HA at GB34 decreased the hepatic HMG-CoA reductase activity in hyperlipidemic rat. 4. AR-HA at GB34 increased the hepatic GSH level in hyperlipidemic rat.
Conclusion : From the above results, it is suggested that AR-HA at GB34 has a therapeutic effect on hyperlipidemia.
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KEYWORD
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Hyperlipidemia, Achyranthis Radix, Herbal-acupuncture, GB34(Yangleungchean)
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