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KMID : 1129720130300010037
Korean Journal of Acupuncture
2013 Volume.30 No. 1 p.37 ~ p.46
Effects of Acupuncture at the River Points(LU8, HT4, PC5, SP5, KI7, LR4) on the Changes of Nitric Oxide Synthase and Norepinephrine in Rats
±è¿µ¼±:Kim Young-Sun
ÃÖµ¿Èñ:Choi Dong-Hee/ÀåÈ£¼±:Jang Ho-Sun/³ªÃ¢¼ö:Na Chang-Su/½ÅÇåÅÂ:Shin Heon-Tae/Á¶ÁÖÇö:Cho Joo-hyun/ÀÌ°æÀÎ:Lee Kyoung-In/±è¼±¹Î:Kim Sun-Min/Ç¥º´½Ä:Pyo Byoung-Sik/À±´ëȯ:Youn Dae-Hwan
Abstract
Objectives : The Meridians and acupuncture points are the fundamental theories for acupuncture therapy. They have been associated with nervous system, but It is not well defined. We investigated that the effects of acupuncture at the river points(LU8, HT4, PC5, SP5, KI7, LR4) on the changes in the expression of nNOS, iNOS, eNOS, and NE in rats.

Methods : The Male Sprague-Dawley rats were divided into 6 groups each non-acupuncture and acupuncture group . We inserted needle and retained for 5 minutes on both left and right sides of LU8, HT4, PC5, SP5, KI7, LR4 which were the river points of five transport points for 6 yin meridian vessels. After that, blood was drawn via cardiac puncture, and tissues for each point near meridian vessels were extracted to examine the changes in the changes of nNOS, eNOS, iNOS and NE.
Results : The LU8 and HT4 group showed a significant decrease on nNOS. In terms of eNOS and iNOS, the LU8 group decreased significantly while the KI7 group increased significantly. However, the experimental groups didn¡¯t show any significant changes on the plasma and tissue norepinephrine without plama NE in SP5 group.

Conclusions : The effect on the nNOS, iNOS, eNOS of acupuncture at LU8 and KI7 could be observed, and it is considered that the effect of acupuncture related with on nervous system could be studied by additional researches based on this one.
KEYWORD
five transport points, river point, nNOS, iNOS, eNOS, norepinephrine(NE)
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