KMID : 1129720140310040188
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Korean Journal of Acupuncture 2014 Volume.31 No. 4 p.188 ~ p.194
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The Study on Pharmacological Activation as Cosmetic Material of Rosa rugosa Thunb. Flowers Extract
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À¯Çý¼ö:Yu Hye-Soo
ÃÖÁöÀº:Choi Ji-Eun/¿ì¿øÈ«:Woo Won-Hong/¹®¿¬ÀÚ:Mun Yeun-Ja
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Abstract
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Objectives : In this study, we investigated the effect of ethanol extract from Rosa rugosa Thunb. flowers(ERF) on the activities of antioxidant, antiwrinkle and whitening.
Methods : We measured antioxidant efficacy of ERF by using 1,1-diphenyl-2- picrylhydrazyl(DPPH) assay. Also we confirmed the inhibitory effect of ERF on collagenase activity and melanin synthesis by using collagenase assay kit and dihydroxiphenylalanine staining, respectively. To evaluate the anti-inflammatory effects of ERF, we examined the inflammatory mediator IL-6.
Results : ERF showed highly efficacy in DPPH radical scavenging activity. ERF dose-dependently suppressed collagenase activity. Ultraviolet-induced production of IL-6 decreased by ERF treatment. In B16F10 cell, ERF significantly reduced tyrosinase activity and melanin synthesis.
Conclusions : From the above results, it was indicated that ERF could be utilized as anti-aging and whitening cosmetic ingredients
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KEYWORD
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Rosa rugosa Thunb flowers, antioxidant, collagenase, melanin
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