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KMID : 1129720190360040189
Korean Journal of Acupuncture
2019 Volume.36 No. 4 p.189 ~ p.199
Effects of Laser and Electro Acupuncture Treatment with GB30.GB34 on Change in Arthritis Rat
Kim Mi-Rae

Lee Yu-Mi
Choi Dong-Hee
Youn Dae-Hwan
Na Chang-Su
Abstract
Objectives : This study aimed to investigate the effects of electroacupuncture (EA), the laser acupuncture (LA) and the combination therapy (LA+EA) in a collagenase-induced osteoarthritis rat model.

Methods : Osteoarthritis rat model was induced by injection of collagenase into left lower articular cavity (50 ¥ìl to knee and 10 ¥ìl to ankle). In order to assess the anti-osteoarthritic effects of EA, the 650 nm LA and 650 nm LA+EA, the histopathological findings and plantar withdrawal responses were analyzed.

Results : All of the treatment methods used in this study were effective in reducing pain. All treatment groups were effective in decreasing inflammatory cytokines of TNF-a and IL-6; the 650 nm LA and 650 nm LA+EA groups significantly reduced IL-1¥â.

Conclusions : 650 nm LA and EA inhibit the production of collagenase-induced inflammatory mediators of osteoarthritis.
KEYWORD
arthritis, laser acupuncture, electro acupuncture, collagenase, combination therapy
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