KMID : 1129720190360040189
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Korean Journal of Acupuncture 2019 Volume.36 No. 4 p.189 ~ p.199
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Effects of Laser and Electro Acupuncture Treatment with GB30.GB34 on Change in Arthritis Rat
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Kim Mi-Rae
Lee Yu-Mi Choi Dong-Hee Youn Dae-Hwan Na Chang-Su
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Abstract
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Objectives : This study aimed to investigate the effects of electroacupuncture (EA), the laser acupuncture (LA) and the combination therapy (LA+EA) in a collagenase-induced osteoarthritis rat model.
Methods : Osteoarthritis rat model was induced by injection of collagenase into left lower articular cavity (50 ¥ìl to knee and 10 ¥ìl to ankle). In order to assess the anti-osteoarthritic effects of EA, the 650 nm LA and 650 nm LA+EA, the histopathological findings and plantar withdrawal responses were analyzed.
Results : All of the treatment methods used in this study were effective in reducing pain. All treatment groups were effective in decreasing inflammatory cytokines of TNF-a and IL-6; the 650 nm LA and 650 nm LA+EA groups significantly reduced IL-1¥â.
Conclusions : 650 nm LA and EA inhibit the production of collagenase-induced inflammatory mediators of osteoarthritis.
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KEYWORD
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arthritis, laser acupuncture, electro acupuncture, collagenase, combination therapy
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