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KMID : 1145320120010010013
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Journal of Korea Immuno-yakchim Society
2012 Volume.1 No. 1 p.13 ~ p.22
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Analysis of physioactivities on I Yakchim
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Kim Hak-Ju
Choi Il-Whan
Jung Chul
Han Ga-Jin
Ko Seok-Jae
Kim Seul-Ki
Park Jae-Woo
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Abstract
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Objectives: The aim of this study is to investigate the contents and physioactivities of I Yakchim.
Methods: In this study, we analyzed the amount of total protein, total glucose, crude fat and crude ash of I Yakchim. The anti-oxidative effect of I Yakchim was analyzed by investigating 1,1-diphenyl-2-picryl hydrazyl free radical scavenging activity. To investigate the anti-inflammatory effect of I Yakchim, cyclooxygenase-2, tumor necrosis factor-α and interleukin-6 were measured.
Results: I Yakchim consists of 0.06% of protein, 0.31% of total glucose, 97.65% of crude fat and 0.61% of crude ash. I Yakchim showed higher anti-oxidative effect compared to butyl hydroxyanisole. I Yakchim also showed anti-inflammatory effect by inhibiting cyclooxygenase-2, tumor necrosis factor-α and interleukin-6.
Conclusions: I Yakchim might have anti-oxidant and anti-inflammatory effect. Further investigation including exact mechanisms should be needed.
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KEYWORD
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Pharmacopuncture, Juglandis Semen, I Yakchim, Antioxidant, Antiinflammatory, Nam Sang Cheon, Immuno Yakchim
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