KMID : 1145320120010010023
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Journal of Korea Immuno-yakchim Society 2012 Volume.1 No. 1 p.23 ~ p.31
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Anti-oxidant and anti-inflammatory effects of HO Yakchim
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Kim Hak-Ju
Choi Il-Whan Jung Chul
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Abstract
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Objectives: The aim of this experimental study was to investigate the component of HO Yakchim and prove its anti-oxidant and anti-inflammatory effect.
Methods: Content of protein, glucose, crude fat and crude ash was calculated. Anti-oxidant effect was measured using DPPH free radical scavenging activity. Anti-inflammatory effect was measured with COX-2 kit and RAW 264.7 macrophage. the concentration of TNF-¥á and IL-6 was measured by Enzyme-linked immuno-sorbent assay.
Results: HO Yakchim is consist of 0.09% of protein, 0.23% of glucose, 97.04% of crude fat and 0.37% of crude ash. HO Yakchim showed better anti-oxidant effect than its BHA control sample. The COX-2 inhibiting capacity of HO Yakchim was better than its Indomethacin control sample. Inflammatory cytokine production was reduced but not at transcription level.
Conclusions: These results represents that HO Yakchim is composed of protein, glucose, crude fat and crude ash. HO Yakchim anti-oxidant and anti-inflammatory effect.
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KEYWORD
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Anti-oxidant effect, Anti-inflammatory effect, HO Yakchim, Carthamus tinctorius, Pharmacopuncture, Nam Sang Cheon, Immuno Yakchim
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