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KMID : 1145320120010010033
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Journal of Korea Immuno-yakchim Society
2012 Volume.1 No. 1 p.33 ~ p.42
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Analysis of physioactivities on HN Yakchim
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Kim Hak-Ju
Choi Il-Whan
Jung Chul
Han Ga-Jin
Ko Seok-Jae
Kim Seul-Ki
Park Jae-Woo
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Abstract
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Objectives: The aim of this study is to investigate the contents and physioactivities of HN Yakchim.
Methods: In this study, we analyzed the amount of total protein, total glucose, crude fat and crude ash of HN Yakchim. The anti-oxidative effect of HN Yakchim was analyzed by investigating 1,1-diphenyl-2-picryl hydrazyl fre radical scavenging activity. To investigate the anti-inflammatory effect of HN Yakchim, cyclooxygenase-2, tumor necrosis factor-α and interleukin-6 were measured.
Results: HN Yakchim consists of 0.05% of protein, 0.27% of total glucose, 97.71% of crude fat and 0.49% of crude ash. HN Yakchim showed relatively higher anti-oxidative effect compared to butyl hydroxyanisole. HN Yakchim also showed anti-inflammatory effect by inhibiting cyclooxygenase-2, tumor necrosis factor-α and interleukin-6.
Conclusions: HN Yakchim might have anti-oxidant and anti-inflammatory effect. Further investigation including exact mechanisms should be needed.
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KEYWORD
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Pharmacopuncture, Cervi parvum cornu, Carthami Semen, HN Yakchim, Antioxidant, Antiinflammatory, Nam Sang Cheon, Immuno Yakchim
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