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KMID : 1145320140030020009
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Journal of Korea Immuno-yakchim Society
2014 Volume.3 No. 2 p.9 ~ p.17
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Screening of Antimicrobial Activity and Bioactivity Effects are Herbal Medicine Extracts of Acne
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Song Chang-Ho
Lim Young-Hoon
Choi Moon-Kyung
Kim Hak-Ju
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Abstract
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Objectives : The aim of this study is screening of effective anti-microbial activity and bio-activity from herbal medicine.
Methods : In this study, analyzed the amount of total sugar, reducing sugar, protein and flavonoid of herbal medicine. Screening of anti-microbial properties of acnes strains. The anti-oxidative effect of herbal medicine was analyzed by investigating 1,1-diphenyl-2-picryl hydrazyl free radical scavenging activity. To investigate the anti-inflammatory effect, cyclooxygenase-2, tumor necrosis factor-a and interleukin-6 were measured.
Results : The anti-microbial activity of 11 herbal medicine extracts. 7 herbal medicine extracts showed relatively higher anti-oxidative and anti-inflammatory effect. Also showed Inhibiting cyclooxygenase-2, tumor necrosis factor-a and interleukin-6.
Conclusions : Herbal medicine extracts have anti-oxidant and anti-inflammatory effect, and inhibition effect of the cyclooxygenase-2, tumor necrosis factor-a and interleukin-6.
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KEYWORD
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Antimicrobial activity, herbal medicine, acne, bioactivity effect
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