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KMID : 1145320140030020019
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Journal of Korea Immuno-yakchim Society
2014 Volume.3 No. 2 p.19 ~ p.30
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Studies on Bioactivity Herbal Medicine Extracts Specific Prescription Acne Treatment
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Song Chang-Ho
Han Jin-Wook
Choi Moon-Kyung
Lim Young-Hoon
Kim Hak-Ju
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Abstract
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Objectives : The aim of this study is bio-activity herbal medicine extracts specific prescription acne treatment.
Methods : In this study, analyzed the amount of total sugar, reducing sugar, protein and flavonoid of herbal medicine. Screening of minimum inhibitory concentration of acnes strains. The anti-oxidative effect of herbal medicine was analyzed by investigating 1,1-diphenyl-2-picryl hydrazyl free radical scavenging activity. To investigate the anti-inflammatory effect, cyclooxygenase-2, tumor necrosis factor-a and interleukin-6 were measured.
Results : The EE extract have higher antimicrobial activity. CE extracts showed relatively higher anti-oxidative effect. All extract have similar anti-inflammatory and Inhibiting cyclooxygenase-2. EE extract have higher inhibition of tumor necrosis factor-a and interleukin-6.
Conclusions : EE extracts have anti-oxidant and anti-inflammatory effect, and inhibition effect of the cyclooxygenase-2, tumor necrosis factor-a and interleukin-6.
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KEYWORD
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Antimicrobial activity, herbal medicine, acne, bioactivity effect
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