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KMID : 1145320150040020037
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Journal of Korea Immuno-yakchim Society
2015 Volume.4 No. 2 p.37 ~ p.45
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Comparative Studies on the Biological Activity of V and A Yakchim
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Lee Ma-Seong
Jung Chul
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Abstract
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Objectives : The purpose of this study was to investigate the equivalence between A Yakchim (AY) and V Yakchim (VY) through anti-oxidant and anti-inflammatory activity.
Methods : In this study, we analyzed the amount of total sugar, reducing sugar, protein, flavonoid and polyphenol of VY and AY. The anti-oxidant activity was determined by assaying the level of radical scavenging activity against 2,2‘-diphenyl-1-picrylhydrazyl (DPPH) and we investigate the anti-inflammatory effect of VY and AY by measuring the production of nitric oxide (NO) in Raw 264.7 cells activated by lipopolysaccharide.
Results : VY (10 mg/ml) and AY (10 mg/ml) showed 4.7±1.7% and 61.7±2.1% of DPPH radical scavenging activity, respectively. And VY (1 mg/ml) and AY (1 mg/ml) decreased 17% and 42% of the NO production, respectively.
Conclusions : These results suggested the possibility that the anti-oxidant activity and anti-inflammatory activity of AY are better than VY.
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KEYWORD
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V Yakchim, A Yakchim, anti-inflammatory effect, anti-oxidant effect, immuno-Yakchim
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