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KMID : 1146520110120010001
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Journal of the Society of Stroke on Korean Medicine
2011 Volume.12 No. 1 p.1 ~ p.7
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Orungsan(Goreisan) Application in Neurosurgical Field: Review of the Studies Reported in the 20th Annual Meeting of Kampo Medicine Association of the Japan Neurosurgical Society
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Jang In-Soo
Kwon Seung-Won
Kim Kying-Wook
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Abstract
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Objectives : The purpose is to discuss the clinical applications of Orungsan(Goreisan: 五?散) as an alternative management for increased intracranial pressure in the field of neurosurgery in Japan.
Methods and Results : Attention has focused on Kampo medicine(traditional Japanese medicine) for some cerebral
disease including chronic subdural hematoma(CSDH) and cerebral infarction in Japan. Orungsan and one of its classes,
Sirungtang(Saireto: 柴?湯) are well known their effects on brain edema. After some studies of Orungsan has the anti-edemic effects by the inhibition of aquaporin, this herbal medicine has been used widely in the neurosurgery field in Japan. It is high time to think about where we are and we go ahead for the progress and the integration in medicine. We have reviewed the studies using Orungsan or Sirungtang , that was reported at the 20th annual meeting of 'the Japan society for Kampo medicine and neurological surgery' was held on November 5, 2011 in Tokyo.
Fifteen studies related with Orungsan or Sirungtang were reported among all 32 studies at the meeting. Orungsan in ten,
and Sirungtang in five among 14 studies contained specific clinical case. In the aspects of disease, thirteen papers were related with SDH, including CSDH(11), SSDH(1), aneurism clipping for SDH prevention(1), and one was acute cerebral infarction and one was multiple metastatic brain tumor. In the report style, case control study was 7(mostly retrospective), and the case report was 8.
Conclusions : Orungsan may be plausible to be an alternative method to reduce brain edema after SDH and other brain injury in the field of neurosurgery.
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KEYWORD
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Goreisan, Saireto, Neurosurgery, Chronic subdural hematoma, Kampo medicine, Japanese medicine
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