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KMID : 1148720200080010049
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2020 Volume.8 No. 1 p.49 ~ p.56
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Effects of Pulmonary Physical Therapy in Patients with Pulmonary Diseases after Hematopoietic Stem Cell Transplantation
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Kim Jae-Yeong
Lee Dong-Hun
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Abstract
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Purpose : The purpose of this study was to determine the effect of pulmonary physical therapy in patients with pulmonary disease after hematopoietic stem cell transplantation (HSCT).
Methods : The subjects were 25 patients who were diagnosed with pulmonary disease after HSCT. We measured forced vital capacity (FVC), forced expiratory volume in one second (FEV1),FEV1/FVC, r esidual volume ( RV), t otal l ung capacity (TLC), R V/TLC, a nd d iffusion c apacity of c arbon monoxide (DLCO). The data were analyzed using one-way repeated analysis of variance with Bonferonni correction post-hoc.
Results : Before pulmonary physical therapy, FVC, FEV1,FEV1/FVCandDLCO were significantly lower than pre-HSCT measurements, and RV and RV/TLC were significantly higher. After pulmonary physical therapy, FVC, FEV1, and DLCO were significantly higher than before pulmonary physical therapy
Conclusion : This study demonstrated that the pulmonary physical therapy was effective in patients with pulmonary disease post-HSCT.
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KEYWORD
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Hematopoietic stem cell transplantation, Pulmonary disease, Pulmonary function, Pulmonary physical therapy
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